I was originally prescribed Glucosamine by my GP, who also used it, for arthritis pain. After a couple of years, he suggested I switch to Lakota, which, he said, also contained Glucosamine, but it was used more efficiently in Lakota? I'm not sure if that's exactly what he said, because this more than 15 years ago, I think, but I'm still using it and have very little to no pain from my arthritis.